Alexander J.
Shackman, Ph.D.

I have three major research
interests.
First, what psychological and
neural mechanisms mediate anxiety's impact on how we think and act?
Accordingly, we have examined the effects of experimentally induced anxiety on
cognitive tasks thought that rely on the prefrontal cortex. We have also sought
to better characterize how individual differences in anxious temperament,
emotion regulation, and working memory capacity can minimize or intensify
threat's impact.
A second line of work seeks
to identify the functional significance of aberrant activity in the prefrontal
cortex of individuals afflicted with major depression. In particular, we are
trying to tease apart the contributions of exaggerated emotional reactivity
from deficient emotion regulation.
A third line of work seeks to
develop more sensitive and specific markers of deception in individuals
committing high-stakes lies.
Common to each of these three
areas is a strong interest in quantitative and physiological methodology.
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